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Indeed, a report aiming to evaluate the role of academia on the identification and development of “ de novo ” or repurposed transformative drugs with groundbreaking effects on patient care pointed to a key role of academic medical centers, often funded by the government and/or by patient associations or foundations, in conceptualizing therapeutic approaches based on preclinical research disease mechanisms, and providing the proof of concept for the utilization of a given molecule for a particular disease (Kesselheim et al., 2015)

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