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212 As an electron donor, NADH produced in the TCA cycle plays a crucial role in ATP synthesis by OXPHOS, which generates most of the energy through the H + gradient in animal cells
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In animals, administration of GH in supraphysiologic doses leads to an increase in many organs, most noticeably, cardiomegaly, which also mimics that seen in acromegaly (Kopchick, Bellush and Coschigano, 1999, Penney, Dunbar and Baylerian, 1985)
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