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3 In controlled laboratory settings, 5-Amino-1MQ may be used to investigate how NNMT modulation affects NAD+ availability, redox balance, and related metabolic pathways
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A small molecule enhancing MET activity (the MET agonist NDX-1017 or ATH-1017) was recently tested in AD patients (NCT03298672), resulting in positive outcomes in terms of brain network activity, even if larger studies need to be performed to show more robust and statistically significant results
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