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BPC-157 and Regenerative Peptides: What We Know, What We Don't, and What Actually Matters | Backcountry Physical Therapy

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Regarding molecular mechanisms, the betalains are able to decrease the protein levels of the proinflammatory cytokines (TNF-α, IL-6, IL-8, and IL-1β), the reactive oxygen species (ROS), nitrogen species, and also the activity of cyclooxygenase-1(COX-1), 5-lipoxygenase (5-LOX), NADPH oxidase-1 (Nox-1) enzymes, leading to the reduction of PGE2 and leukotrienes level (Ninfali et al., 2017