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LMA, a major component of codonopsis lanceolata, displays antioxidant effects not only by downregulating ROS production via inhibiting expression/phosphorylation of NOX subunits but also by inhibiting the activation of JNK and NF-κB pathway (190)

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However, STP2 , a transcription factor that regulates expression of amino acid permeases seemed to play an important role given that a stp2 ΔΔ mutant showed attenuated cytotoxic potential (Fig