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For instance, the Kla of aldolase A (ALDOA) is present in numerous human tumor cell lines and can control glycolysis through controlling the activity of metabolic enzymes ( 4 Lactylation promoting the occurrence and development of tumors 4.1 Lactylation affecting the metabolism of tumor cells The metabolic reprogramming of tumor cells, which promotes rapid cell growth and proliferation through altering the metabolism, is considered to represent a new cancer characteristic ( Hypoxia-inducible factor alpha (HIF-1α) is a key gene that regulates the metabolic mode of tumor cells ( Wan et al
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