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LA also lowered the levels of MDA and nitrite in the 6-OHDA-induced rat model of hemi-parkinsonism (Jalali-Nadoushan and Roghani, 2013)
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Beyond direct epithelial protection, LXA4/FPR2 signaling suppresses CXCL1 release, thereby limiting neutrophil trafficking from the circulation into the alveolar compartment ( in vivo and in vitro , and notably, the p38 MAPK inhibitor SB203580 similarly reverses CSE-induced inflammation and ferroptosis (Li J
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