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A strong positive effect of NaBPC157 is evident in both pre-treatment (1 hour before ligation) as well as post-treatment (1 hour after ligation) applications
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As many naevomelanocytes in cutaneous naevi show activating mutations in the BRAF or in the NRAS intracellular signalling pathways which mediate cell proliferation and differentia-tion [11, 34, 42], naevi are considered by many to be benign naevomelanocytic neoplasias
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