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Pre-treatment of THP-1 cells with 5 μ M CBR-470–1 for 18 h ( Figure 4C ), a protein kinase G (PKG) inhibitor that promotes glycolytic flux and endogenous MG accumulation ( Figure 4D )
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1), and their role in health and disease, in this review, we reflect on advancements made and lessons learned in the estrobolome field during the past 15 years
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